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muciniphila may influence glucose metabolism, noting that the bacterium produces propionate (another SCFA) that can stimulate GLP-1 secretion through free fatty acid receptor signaling
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Those who are not tolerating the maximal dose, or are switching to a once-weekly GLP-1 receptor agonist because of GI adverse effects, should stop the once-daily medication and wait until their symptoms have resolved before starting the lowest dose of the chosen weekly GLP-1 receptor agonist