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Despite FDA ruling, compounded GLP-1s are still giving Novo and Lilly headaches on the market

While this delayed transit contributes to the medication's therapeutic benefits, it can lead to uncomfortable bowel changes that impact treatment adherence

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84 , 85 Nevertheless, the majority of clinical trials in these areas are small, exploratory, enroll different patients, and use different medicines and endpoints, precluding generalization of limited clinical observations to date