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Compounding the issue, many commonly prescribed psychotropic medications, including second-generation antipsychotics, mood stabilizers, and certain antidepressants, are known to worsen metabolic parameters [50,51,52,53]
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In neonatal rat cardiomyocytes, BBR decreased hypoxia-reoxygenation-stimulated cardiomyocytes apoptosis, increased Bcl-2/Bax ratio, activated PI3K-Akt, AMPK and eNOS phosphorylation, while decreased caspase-3 expression 173 , 174
